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congres neurochirurgiePublié le 25/01/2015
PARIS 26 mars 2018 expertise neuro onco.
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Je vais passer une mammographie
La mammographie est un examen utilisé dans le dépistage et le diagnostic des affections du sein. Elle peut permettre notamment de détecter précocement un cancer.Lire la suite
Role of surgery, radiotherapy and chemotherapy in papillary tumors of the pineal region: a multicenter study
Papillary tumor of the pineal region (PTPR), recently described as a distinct clinicopathological entity, can show aggressive biological behavior. The optimal therapeutic approach of PTPR has not been well defined. The role of surgery, radiotherapy, and chemotherapy in the treatment of PTPR was analyzed in a large multicenter series. In order to determine factors that influence prognosis, outcome data of a series of 44 patients with histopathologically proven PTPR were retrospectively analyzed. Of the 44 patients, 32were still alive after a median follow-up of 63.1 months. Twelve patients experienced progressive disease, with seven undergoing two relapses and five more than two. Median overall survival (OS) was not achieved. Median progression-free survival (PFS) was 58.1 months. Only gross total resection and younger age were associated with a longer OS, radiotherapy and chemotherapy having no significant impact. PFS was not influenced by gross total resection. Radiotherapy and chemotherapy had no significant effect. This retrospective series confirms the high risk of recurrence in PTPR and emphasizes the importance of gross total resection. However, our data provide no evidence for a role of adjuvant radiotherapy or chemotherapy in the treatment of PTPR. Keywords Papillary tumor of the pinLire la suite
traitement des tumeurs de la région pinéale - Treatment of pineal region tumours : a review
mise à jour des experts. Pineal region tumours affect children and adults and belong to numerous and various entities. The tumour site is relatively easy to localise nowadays with modern imaging techniques. However histopathological diagnosis remains however difficult: it depends on well-defined criteria for each entity. Three histological groups are usually recognised according to the WHO classification for pineal parenchymal tumours (PPT): pineocytoma, pineoblastoma and PPT with intermediate differentiation. We propose a new classification with 4 histological grades correlated to survival. The treatment for each tumour type is different. Germ cell tumours are treated with chemotherapy and irradiation of the ventricular system, leading to an average complete remission rate of 90 %. Mixed germ cells tumours, with or without tumour marker secretion, are treated initially with chemotherapy (carboplatine, VP 16 and Ifosfamide), and followed by surgery of a possible tumour remnant and focal irradiation. Treatment of other entities depends above all on surgery which can lead to significant tumour specimens for histology purposes and complete resection in many cases. This treatment allows complete remission of benign cystic tumours and pineocytomas. For malignant PPT, radiotherapy should be added to surgery but prognosis remains uncertain. For pineoblastomas, a combination of surgery, radiotherapy and chemotherapy is mandatory. Long-term follow up is useful for the detection of neurocognitive deficit, and of early (germinal tumours) or late recurrences (PPT). Key words: pineal region tumour, germ cell tumour, primitive parenchymal pineal tumour, ependymoma, radiotherapy, chemotherapy, brain tumour.Lire la suite
radiothérapie des tumeurs cérébrales
Actualité du traitement des tumeurs cérébrales 2014Lire la suite
Cancer de l’œsophage : je comprends mon traitement
Le traitement du cancer de l’œsophage dépend de l’avancement de votre maladie et de votre état de santé. Il peut faire appel à une chirurgie, une radiothérapie et une chimiothérapie.Lire la suite